Opaleye Management Inc.
Opaleye Management Inc. has made 13 open-market purchases worth $2.6M since Sep 16, 2026, in 2 companies. The latest: $159k of GRCE, filed Oct 26, 2026, scored 14 out of 100.
10% owner, Grace Therapeutics, Inc. 10% owner, Alpha Cognition Inc.
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Purchases
| Filed | Stock | Stake | Score | Bought | 1 week | 1 month |
|---|---|---|---|---|---|---|
| Oct 26 Form 4 (opens sec.gov) |
GRCEGrace Therapeutics, Inc. · 10% owner10% owner · Near 52-week low · Penny stock: hard to trade | +3% stake | 14 | $159k 87,801 at $1.81 |
waiting | waiting |
| Oct 26 Form 4 (opens sec.gov) |
ACOGAlpha Cognition Inc. · 10% owner10% owner | +1% stake | 23 | $266k 32,090 at $8.28 |
waiting | waiting |
| Oct 21 Form 4 (opens sec.gov) |
GRCEGrace Therapeutics, Inc. · 10% owner10% owner · Near 52-week low · Penny stock: hard to trade | +0% stake | 6 | $8k 4,256 at $1.88 |
— | — |
| Oct 19 Form 4 (opens sec.gov) |
ACOGAlpha Cognition Inc. · 10% owner10% owner | +1% stake | 23 | $309k 36,940 at $8.35 |
+3.5% | waiting |
| Oct 17 Form 4 (opens sec.gov) |
GRCEGrace Therapeutics, Inc. · 10% owner10% owner · Near 52-week low · Penny stock: hard to trade | +3% stake | 14 | $136k 71,065 at $1.92 |
−3.7% | waiting |
| Oct 13 Form 4 (opens sec.gov) |
GRCEGrace Therapeutics, Inc. · 10% owner10% owner · Near 52-week low | +1% stake | 12 | $30k 14,632 at $2.03 |
+4.2% | waiting |
| Oct 5 Form 4 (opens sec.gov) |
GRCEGrace Therapeutics, Inc. · 10% owner10% owner · Near 52-week low | +2% stake | 16 | $124k 60,490 at $2.05 |
−3.6% | waiting |
| Oct 2 Form 4 (opens sec.gov) |
ACOGAlpha Cognition Inc. · 10% owner10% owner · Near 52-week high | +1% stake | 24 | $166k 19,050 at $8.69 |
−3.4% | waiting |
| Oct 1 Form 4 (opens sec.gov) |
GRCEGrace Therapeutics, Inc. · 10% owner10% owner · Near 52-week low | +0% stake | 12 | $16k 7,849 at $2.09 |
— | — |
| Oct 1 Form 4 (opens sec.gov) |
GRCEGrace Therapeutics, Inc. · 10% owner10% owner · Near 52-week low · Filed late | +1% stake | 0 | $32k 15,089 at $2.10 |
+0.5% | waiting |
| Sep 28 Form 4 (opens sec.gov) |
ACOGAlpha Cognition Inc. · 10% owner10% owner · Near 52-week high | +1% stake | 27 | $271k 31,763 at $8.53 |
+3.1% | +5.5% |
| Sep 23 Form 4 (opens sec.gov) |
GRCEGrace Therapeutics, Inc. · 10% owner10% owner · Near 52-week low | +1% stake | 12 | $32k 15,089 at $2.10 |
−5.6% | −16.2% |
| Sep 16 Form 4 (opens sec.gov) |
ACOGAlpha Cognition Inc. · 10% owner10% owner · Near 52-week high | +4% stake | 34 | $1.1M 123,918 at $8.57 |
−3.2% | −4.0% |
Track record (hypothetical): a week after the filing, these buys averaged −0.9% (44% up, 9 measured); a month after, −4.9% (33% up, 3 measured).
Questions
What stock has Opaleye Management Inc. bought?
GRCE (Grace Therapeutics, Inc.), ACOG (Alpha Cognition Inc.), all on the open market and reported on SEC Form 4.
When did Opaleye Management Inc. last buy?
Oct 26, 2026: 87,801 shares of GRCE at $1.81, $159k in all (Form 4 (opens sec.gov)).
Has Opaleye Management Inc. filed a notice of a planned sale?
Not in the filings on record. A Form 144 is the notice an insider must file before selling restricted or control shares, and it lands on EDGAR before the sale is reported.
Is Opaleye Management Inc. a routine or an opportunistic buyer?
There isn't enough history to say yet.
Data as of Oct 26, 2026, from SEC EDGAR Form 4 filings: open-market purchases (code P) of $25,000 or more, and open-market sales. Every row links to its filing. Scores summarise what a filing says (how the score works); outcomes are hypothetical, from the first close after the filing, and past results don't predict future ones. Disclaimer